Peptide Database

Peptide NamehBD-28

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC176H288N54O48S7

DescriptionStandard

        AKPKRCFNNVSGYCRKKCKMGEIAEVGCLHAKYCCVN
    

Molecular Weight4152.96 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.82

Net Charge (pH 7.4) 5.48

Charge Density (pH 7.0) 0.1573

GRAVY Index-0.36

Hydrophobic Moment 0.60

Boman Index-0.14

Instability Index27.06

Aliphatic Index 52.70

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1675.29

LogP -17.54

H-bond Donors 64.0

H-bond Acceptors 62.0

Rotatable Bonds 141.0

Heavy Atoms 285.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0292238 VERIFIED: YES

Provenance & Taxonomy

OrganismMicrotus ochrogaster [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)