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MYP_114521
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Basic Information
Nigrocin-2ISa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
21 amino acids
C90H155N23O24S2
Standard
Sequence
GILGTVFKAGKGIVCGLTGLC
Physicochemical Analysis
2007.46 Da
8.90
1.74
1.50
0.0828
1.28
0.49
0.49
-16.76
125.24
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
737.82
-6.43
28.0
28.0
67.0
139.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010428 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0014466 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
50 μM
MIC
PaperIdentification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae
RECORD: Rec_0043303 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 23.8%, E 9.5%, T 33.3%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0047309 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Nigrocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 8739
50 μM
MIC
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
RECORD: Rec_0050579 VERIFIED: YES
Provenance & Taxonomy
Endangered frog [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
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