Peptide Database

Peptide NameSLAY-screened peptide P4587

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC30H52N6O9

DescriptionStandard

        PPTILT
    

Molecular Weight640.77 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0069

GRAVY Index0.62

Hydrophobic Moment 0.29

Boman Index0.43

Instability Index72.53

Aliphatic Index 130.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 226.50

LogP -1.39

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 16.0

Heavy Atoms 45.0

Ring Count 2.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360826 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/