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MYP_114491
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Basic Information
Enterocin L50A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
44 amino acids
C252H392N60O54S2
Standard
Sequence
MGAIAKLVAKFGWPIVKKYYKQIMQFIGEGWAINKIIEWIKKHI
Physicochemical Analysis
5190.31 Da
10.00
5.58
5.30
0.1269
0.20
0.77
0.24
26.64
110.91
0.1591
19480.00
19480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1834.37
-2.68
63.0
63.0
176.0
368.0
12.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0185426 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
EntL50 activity was maximally accumulated at 16 to 25°C and was not detected at 37°C or above. leaderless, i.e. no signal peptide. The sequence of chain b (EntL50B) is MGAIAKLVFKFGWPLIKKFYKQIMQFIGQGWTIDQIEKWLKRH. Chemical modification: The N-terminal Met is formylated
Bio-Activity Profile
Antimicrobial
PaperEnterocins L50A and L50B, two novel bacteriocins from Enterococcus faecium L50, are related to staphylococcal hemolysins
RECORD: Rec_0216936 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
1352
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus sake 148
PaperLiao W, Ma D, Wang R, Han Z, Shao T, Li H, Liu S (2009) mRNA Cloning, Evolutionary Analysis and Biological Characterization of Duck Avian Beta-defensin 10. Acta Veterinaria et Zootechnica Sinica, 2009, 40(9): 1320-1326; 35260685 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0218148 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium],L50 [Bacterium]
Enterocin
1352
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 9555877 PMID9555877 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9555877/
RECORD: Rec_0243884 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium],L50 [Bacterium]
Enterocin
1352
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterococcus faecium T136(1200AU/ml)
PaperPubMed PMID: 9555877 | PubMed PMID: 20398277 PMID9555877;20398277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9555877/
RECORD: Rec_0301081 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium],L50 [Bacterium]
Enterocin
1352
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
cremoris CNRZ 177(4800AU/ml)
PaperPubMed PMID: 9555877 | PubMed PMID: 20398277 PMID9555877;20398277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9555877/
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