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MYP_114488
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Basic Information
Mastoparan-like peptide 12b (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
13 amino acids
C70H120N18O15S
Standard
Sequence
INWKGIAAMKKLL
Physicochemical Analysis
1485.88 Da
10.30
2.76
2.55
0.2121
0.43
0.44
0.21
-18.34
135.38
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
549.46
-1.19
19.0
19.0
52.0
104.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0263781 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 2592
3.7 μg/mL
MIC
PMID16330062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
RECORD: Rec_0265174 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Staphylococcus aureus
PMID16330062;17046111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
RECORD: Rec_0276090 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 2002
7.5 μg/mL
MIC
PMID16330062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
RECORD: Rec_0307113 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 2592
3.7 μM
MIC
PaperAntimicrobial peptides from the venoms of Vespa bicolor Fabricius.
RECORD: Rec_0359055 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Mastoparan
202807
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperToxicon. 2006 Feb;47(2):249-53. Epub 2005 Dec 5. | http://www.ncbi.nlm.nih.gov/pubmed/16330062 PMID16330062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
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