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MYP_114446
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Basic Information
Cycloviolacin O19 (cyO19)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Insecticidal/Pest control ▸ Insecticidal activity
Standard
31 amino acids
C138H223N35O43S6
Standard
Sequence
GTLPCGESCVWIPCISSVVGCSCKSKVCYKD
Physicochemical Analysis
3252.85 Da
7.77
0.70
0.40
0.0227
0.47
0.34
0.18
30.47
75.16
0.0645
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1228.80
-14.07
49.0
50.0
102.0
222.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171622 VERIFIED: YES
Provenance & Taxonomy
Viola odorata L. and Viola tricolor L [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
10 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0174624 VERIFIED: NO
Provenance & Taxonomy
Viola odorata [Plant]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-21; 9-23; 14-28
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0222551 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21; 9-23; 14-28
Bio-Activity Profile
Insecticidal
PaperPubMed PMID: 16872274 PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0232127 VERIFIED: YES
Provenance & Taxonomy
Viola odorata L. and Viola tricolor L [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
20 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0239910 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium culmorum
1.5 μM
MIC
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
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