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MYP_114446
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Basic Information
Cycloviolacin O19 (cyO19)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Insecticidal/Pest control ▸ Insecticidal activity
Standard
31 amino acids
C138H223N35O43S6
Standard
Sequence
GTLPCGESCVWIPCISSVVGCSCKSKVCYKD
Physicochemical Analysis
3252.85 Da
7.77
0.70
0.40
0.0227
0.47
0.34
0.18
30.47
75.16
0.0645
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1228.80
-14.07
49.0
50.0
102.0
222.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027334 VERIFIED: YES
Provenance & Taxonomy
Viola odorata L. and Viola tricolor L [Plant]
Cyclotide
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
10 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0029161 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
10 μM
MIC
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0047425 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
20 μM
MIC
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0063258 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Also, plant fungi Fusarium oxysporum
12.5-25 μM
MIC
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. PMID16872274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0065506 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
97441
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Insecticidal Enzymatic-digestion
PaperA novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability | PubMed PMID 28669760 PMID28669760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669760/
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