Peptide Database

Peptide NameRN3(5-17P22-36)[W8I]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC166H263N55O39S

DescriptionStandard

        RPFTRAQIFAIQHISPRTIAMRAINNYRWR
    

Molecular Weight3685.27 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.85

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.1949

GRAVY Index-0.49

Hydrophobic Moment 0.47

Boman Index-0.18

Instability Index60.23

Aliphatic Index 78.33

Aromaticity 0.1333

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1558.79

LogP -13.73

H-bond Donors 57.0

H-bond Acceptors 47.0

Rotatable Bonds 117.0

Heavy Atoms 261.0

Ring Count 8.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267590 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

TargetMRC-5

Activity150 μM

MethodIC50

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