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MYP_114404
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Basic Information
RN3(5-17P22-36)[W8I]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C166H263N55O39S
Standard
Sequence
RPFTRAQIFAIQHISPRTIAMRAINNYRWR
Physicochemical Analysis
3685.27 Da
12.00
5.85
5.59
0.1949
-0.49
0.47
-0.18
60.23
78.33
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1558.79
-13.73
57.0
47.0
117.0
261.0
8.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026315 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes: >150 μM
50 %
Hemolysis
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0151152 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
0.25
ED50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0164524 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
171.55
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0169006 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>150 μM
IC50
PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
RECORD: Rec_0206172 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
171.55±1.23 μM
IC50
PaperPubMed PMID: 29763807 PMID29763807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29763807/
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