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MYP_114380
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
50 amino acids
C233H371N65O78S4
Standard
Sequence
CETWRTETTGATGQASSLLSGRLLEQKAASCHNSYIVLCIENSFMTSFSK
Physicochemical Analysis
5459.09 Da
6.74
-0.17
-0.48
-0.0035
-0.15
0.40
0.03
37.55
68.40
0.0800
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2334.54
-30.48
87.0
83.0
182.0
380.0
6.0
53.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0097404 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0126355 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Endostatin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Literature reports oxidized IVox variant with an intramolecular disulfide bond
Oxidized IVox disulfide-containing variant reported.
Bio-Activity Profile
Anti-angiogenic
PaperAnti-angiogenic peptides for cancer therapeutics PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0179924 VERIFIED: YES
Provenance & Taxonomy
Collagen XVIII [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0199901 VERIFIED: YES
Provenance & Taxonomy
Collagen XVIII [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0271621 VERIFIED: YES
Provenance & Taxonomy
Collagen XVIII [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
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