Peptide Database

Peptide NameLeuprolide

Function Ontology

Anticancer

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC52H74N14O11

DescriptionStandard

        PHWSYLLR
    

Molecular Weight1071.23 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)1.04

Net Charge (pH 7.4) 0.94

Charge Density (pH 7.0) 0.1306

GRAVY Index-0.59

Hydrophobic Moment 0.52

Boman Index0.03

Instability Index29.23

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 399.86

LogP -0.80

H-bond Donors 16.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 77.0

Ring Count 5.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249143 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEnzyme

Tax ID32630

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory Hormone replacement

Half-LifeApproximately 3 hours