Peptide Database

Peptide NameSLAY-screened peptide P5511

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC104H161N31O27S3

DescriptionStandard

        FTPCRPLCDLDIPARNRCPW
    

Molecular Weight2373.78 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.48

Charge Density (pH 7.0) 0.0366

GRAVY Index-0.39

Hydrophobic Moment 0.45

Boman Index-0.14

Instability Index47.54

Aliphatic Index 63.50

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 920.47

LogP -7.46

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 67.0

Heavy Atoms 165.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116627 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/