Peptide Database

Peptide NameLebocin-like anionic peptide 1

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC215H334N58O68

DescriptionStandard

        EADEPLWLYKGDNIERAPTTADHPILPSIIDDVKLDPNRRYA
    

Molecular Weight4819.30 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-4.07

Net Charge (pH 7.4) -4.30

Charge Density (pH 7.0) -0.0969

GRAVY Index-0.77

Hydrophobic Moment 0.56

Boman Index-0.11

Instability Index70.21

Aliphatic Index 90.71

Aromaticity 0.0714

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2017.71

LogP -16.88

H-bond Donors 67.0

H-bond Acceptors 65.0

Rotatable Bonds 151.0

Heavy Atoms 341.0

Ring Count 10.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418019 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

Tax ID7137

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

Targetfilamentous fungi A. niger and T. harzianum

Activity90.9 μM

MethodMIC

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