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MYP_114309
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Basic Information
Lebocin-like anionic peptide 1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
42 amino acids
C215H334N58O68
Standard
Sequence
EADEPLWLYKGDNIERAPTTADHPILPSIIDDVKLDPNRRYA
Physicochemical Analysis
4819.30 Da
4.51
-4.07
-4.30
-0.0969
-0.77
0.56
-0.11
70.21
90.71
0.0714
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2017.71
-16.88
67.0
65.0
151.0
341.0
10.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142228 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0185452 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Lebocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0188131 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Lebocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Listeria monocytogenes (Gram-positive)
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0191673 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0194916 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
L. monocytogenes
90.9 μM
MIC
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