Peptide Database

Peptide NameColicin-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC818H1293N229O255S4

DescriptionStandard

        MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDR
    

Molecular Weight18543.66 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-5.38

Net Charge (pH 7.4) -5.68

Charge Density (pH 7.0) -0.0309

GRAVY Index-0.32

Hydrophobic Moment 0.64

Boman Index0.05

Instability Index49.99

Aliphatic Index 82.87

Aromaticity 0.0575

Extinction Coeff. Reduced 31970.00

Extinction Coeff. Oxidized 31970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7657.30

LogP -84.73

H-bond Donors 259.0

H-bond Acceptors 255.0

Rotatable Bonds 593.0

Heavy Atoms 1306.0

Ring Count 33.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168618 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli KTE73 [Bacterium]

FamilyPyocin/Colicin

Tax ID1182680

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli