Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC413H669N97O101S6

DescriptionStandard

        MKKTLFSVIMLILGIFFVVTPDAASMLGVNTYAAMKIVDAIMAGMSIWSIIGLVAVSGGALAVVWFGVKELIQRVGKKAAIAW
    

Molecular Weight8801.71 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0421

GRAVY Index1.23

Hydrophobic Moment 0.74

Boman Index0.47

Instability Index12.07

Aliphatic Index 132.77

Aromaticity 0.0964

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3086.27

LogP -14.35

H-bond Donors 109.0

H-bond Acceptors 111.0

Rotatable Bonds 291.0

Heavy Atoms 617.0

Ring Count 12.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090023 VERIFIED: NO

Provenance & Taxonomy

OrganismGranulicatella sp. zg-ZJ [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal