Peptide Database

Peptide NameBrevinin-2TC

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC144H235N39O36S4

DescriptionStandard

        GLWESIKNFGKKFALNMMNKIKCKIGGGC
    

Molecular Weight3216.91 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.49

Charge Density (pH 7.0) 0.1633

GRAVY Index-0.13

Hydrophobic Moment 0.69

Boman Index0.07

Instability Index20.32

Aliphatic Index 70.69

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1236.83

LogP -9.79

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 115.0

Heavy Atoms 223.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025454 VERIFIED: YES

Provenance & Taxonomy

OrganismRana kukunoris [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)