Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC748H1170N224O219S6

DescriptionStandard

        MARVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEEGRDEMAVGSHAKGHNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGAVLRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16997.05 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.19

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0145

GRAVY Index-0.53

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index44.60

Aliphatic Index 74.24

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7160.67

LogP -73.09

H-bond Donors 252.0

H-bond Acceptors 235.0

Rotatable Bonds 571.0

Heavy Atoms 1197.0

Ring Count 28.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068502 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage C5 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0344241 VERIFIED: NO