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MYP_114238
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Basic Information
Cyanovirin-N
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
101 amino acids
C470H747N133O164S4
Standard
Sequence
LGKFSQTCYNSAIQGSVLTSTCERTNGGYNTSSIDLNSVIENVDGSLKWQPSNFIETCRNTQLAGSSELAAECKTRAQQFVSTKINLDDHIANIDGTLKYE
Physicochemical Analysis
11013.01 Da
5.02
-3.17
-3.51
-0.0314
-0.45
0.47
-0.03
32.53
75.35
0.0693
9970.00
10220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4887.20
-65.59
172.0
166.0
372.0
771.0
10.0
115.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009692 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID12614152 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12614152/
RECORD: Rec_0027999 VERIFIED: YES
Provenance & Taxonomy
Nostoc ellipsosporum [Bacterium]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 9210678 | PubMed PMID: 9665171 PMID9210678;9665171 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9210678/
RECORD: Rec_0037677 VERIFIED: YES
Provenance & Taxonomy
Nostoc ellipsosporum [other]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Simian immunodeficiency virus
PMID9210678 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9210678/
RECORD: Rec_0093665 VERIFIED: YES
Provenance & Taxonomy
Nostoc ellipsosporum [Bacterium]
Lectin
45916
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
8-22, 58-73
Bio-Activity Profile
Antiviral Anti-HIV
Human immunodeficiency virus (HIV)
0-0.001 μM
EC50
PaperThe antiviral protein cyanovirin-N: the current state of its production and applications. PMID20162270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20162270/
RECORD: Rec_0139788 VERIFIED: YES
Provenance & Taxonomy
Nostoc ellipsosporum [Protist]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
PaperDiscovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.
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