Peptide Database

Peptide NameAmylin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC159H261N49O54S2

DescriptionStandard

        CNTATCATQRLANFLVRTSNNLGAILSPTNVGSNTY
    

Molecular Weight3787.20 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0483

GRAVY Index-0.02

Hydrophobic Moment 0.67

Boman Index0.05

Instability Index7.40

Aliphatic Index 81.39

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1700.76

LogP -25.89

H-bond Donors 61.0

H-bond Acceptors 58.0

Rotatable Bonds 120.0

Heavy Atoms 264.0

Ring Count 3.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024650 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0037236 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyCalcitonin

Tax ID9615

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide

RECORD: Rec_0208336 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyIslet amyloid polypeptide

Tax ID9615

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Analgesic Pronociceptive Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour