Peptide Database

Peptide NameAlpha-defensin 21 (Defensin-related cryptdin-21)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC445H725N137O143S7

DescriptionStandard

        MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR
    

Molecular Weight10506.80 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0156

GRAVY Index-0.48

Hydrophobic Moment 0.70

Boman Index-0.15

Instability Index58.88

Aliphatic Index 80.75

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4592.66

LogP -53.20

H-bond Donors 166.0

H-bond Acceptors 150.0

Rotatable Bonds 356.0

Heavy Atoms 732.0

Ring Count 9.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378906 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic