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MYP_114106
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Basic Information
Signiferin-4.2
Antimicrobial
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
15 amino acids
C77H115N17O21
Standard
Sequence
GFADLFGKAVDFIKS
Physicochemical Analysis
1614.84 Da
5.96
-0.24
-0.45
-0.0160
0.54
0.60
0.29
-22.69
84.67
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
617.59
-3.84
21.0
21.0
53.0
115.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096944 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Signiferin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
nNOS inhibitor
PaperR.J. Jackway et al. / Regulatory Peptides 151 (2008) 80-87. Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: structure, activity and evolutionary trends Evidence URLhttps://www.uniprot.org/uniprotkb/P86134/entry
RECORD: Rec_0213224 VERIFIED: NO
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Enzyme inhibitory
RECORD: Rec_0292622 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/