‹ ›
MYP_114083
← PREVIOUS NEXT → BACK
Basic Information
Caerulein-precursor fragment CPF-B1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C126H218N36O34S2
Standard
Sequence
GLGSLLGKAFKIGLKTVGKMMGGAPREQ
Physicochemical Analysis
2845.43 Da
10.46
3.76
3.55
0.1342
0.04
0.56
0.13
12.17
87.14
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1127.06
-10.63
39.0
40.0
101.0
198.0
2.0
28.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0353525 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Gastrin cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Escherichia coli
PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
RECORD: Rec_0357106 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Gastrin cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Acinetobacter baumannii
PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
RECORD: Rec_0374538 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
5.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part C 152 (2010) 467-472. Antimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
RECORD: Rec_0378878 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part C 152 (2010) 467-472. Antimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
RECORD: Rec_0379123 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Gastrin cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Candida albicans
PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4