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MYP_114083
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Basic Information
Caerulein-precursor fragment CPF-B1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C126H218N36O34S2
Standard
Sequence
GLGSLLGKAFKIGLKTVGKMMGGAPREQ
Physicochemical Analysis
2845.43 Da
10.46
3.76
3.55
0.1342
0.04
0.56
0.13
12.17
87.14
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1127.06
-10.63
39.0
40.0
101.0
198.0
2.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0179771 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part C 152 (2010) 467-472. Antimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
RECORD: Rec_0181313 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
200 μM
LC50
PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
RECORD: Rec_0198047 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID19678697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19678697/
RECORD: Rec_0235346 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
MRSA as well
PaperAntimicrobial peptides with therapeutic potential from skin secretions of the Marsabit clawed frog Xenopus borealis (Pipidae)
RECORD: Rec_0316306 VERIFIED: YES
Provenance & Taxonomy
Xenopus borealis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
25 μM
MIC
PMID20656059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20656059/
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