Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC182H312N70O44S6

DescriptionStandard

        VRNHVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
    

Molecular Weight4377.26 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)8.85

Net Charge (pH 7.4) 8.45

Charge Density (pH 7.0) 0.2328

GRAVY Index-0.33

Hydrophobic Moment 0.76

Boman Index-0.26

Instability Index35.43

Aliphatic Index 74.21

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1861.96

LogP -21.66

H-bond Donors 74.0

H-bond Acceptors 61.0

Rotatable Bonds 142.0

Heavy Atoms 302.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0015774 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)