Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length530 amino acids

Chemical FormulaC2522H3928N694O796S21

DescriptionStandard

        MGRRVITHGRGQALDGDKTTTGAKCISSLPNVKNCGKGVVRLGDRTTVCPKCSKPGTIITGELSVSYGGSPAAVDGSFVMCGCPMGTNRVIAPIGQVSISEELSQSHANNDFLPQQPPPPMPVFAKSCLRGMGCTDAGTSPEPSQNFMPVGYFMATPFSGDDQYNTQHIADNTSLNNSLAESEQHVETAATFPVGAVVFSWISGQFSTVGTWGAKSAASNIGEILVGGAGAPVAAFLVAMMPGKLNSGEQDFIDKMRLSQIADIEGTAPTRVRFAWEEQADGHMMPTGYHTDANGGWDQVPVRNMVLNSQTGNYEFTTEGIKPITIYWNPAKLDFEFKNNTGNQEPLNLPPTITVTPIPEETGGYIETYPADEKNFSDYILILPIPDIPPIYIYFSKPDVNFLEVDLYENFKGRSRQQKYQVDHIPSAAAVKANLKENNPDLTTSELNEKVGRVASIAVPRNTHLYDSETYGGRNNEGQIAKDAKDLRAAADSNFNAIIPSLKNEGATSEQIENARKRIHKLNEEQGLYK
    

Molecular Weight57379.70 Da

Isoelectric Point (pI)5.22

Net Charge (pH 7.0)-13.72

Net Charge (pH 7.4) -14.64

Charge Density (pH 7.0) -0.0259

GRAVY Index-0.41

Hydrophobic Moment 0.75

Boman Index0.03

Instability Index38.67

Aliphatic Index 71.25

Aromaticity 0.0774

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51840.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233335 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0296219 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)