Peptide Database

Peptide NamePleurain-E1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC132H216N38O29S

DescriptionStandard

        AKAWGIPPHVIPQIVPVRIRPLCGNV
    

Molecular Weight2831.43 Da

Isoelectric Point (pI)10.86

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.62

Charge Density (pH 7.0) 0.1105

GRAVY Index0.46

Hydrophobic Moment 0.36

Boman Index0.24

Instability Index30.65

Aliphatic Index 127.31

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1027.34

LogP -5.38

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 82.0

Heavy Atoms 200.0

Ring Count 8.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346358 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pleuraden [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus

Activity6 μg/mL

MethodMIC

RECORD: Rec_0351213 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pleuraden [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity6.3 μg/mL

MethodMIC

RECORD: Rec_0354417 VERIFIED: YES

Provenance & Taxonomy

OrganismRana pleuraden [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetGram-negative bacterium: Escherichia coli

Activity25 μg/mL

MethodMIC

RECORD: Rec_0418424 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative Antioxidant

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