Peptide Database

Peptide NameSLAY-screened peptide P34

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC79H117N23O22S3

DescriptionStandard

        YASHCPCRTICYHVSP
    

Molecular Weight1837.11 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)0.90

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0564

GRAVY Index-0.06

Hydrophobic Moment 0.40

Boman Index0.06

Instability Index66.67

Aliphatic Index 48.75

Aromaticity 0.1250

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 702.65

LogP -7.35

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 50.0

Heavy Atoms 127.0

Ring Count 6.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135919 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/