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MYP_113973
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Basic Information
Acidic phospholipase A2 PnPLA2 (svPLA2; Reptiles, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
DLLQFXDMMK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008649 VERIFIED: YES
Provenance & Taxonomy
Porthidium nasuta [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 22251437 PMID22251437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22251437/
RECORD: Rec_0141305 VERIFIED: YES
Provenance & Taxonomy
Porthidium nasutum [Animal]
Phospholipase A2; Group II subfamily
Structure & Mods
linear peptide [Linear]
noncanonical or undefined residue-containing peptide [Modified]
Undefined residue X at positions 6
Bio-Activity Profile
Antimicrobial Hydrolase Antiplatelet Cytolytic Toxin Cytotoxic Hemolytic
PMID22251437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22251437/
RECORD: Rec_0159841 VERIFIED: YES
Provenance & Taxonomy
Porthidium nasuta [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
aureus ATCC 29213
PaperPubMed PMID: 22251437 PMID22251437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22251437/
RECORD: Rec_0303345 VERIFIED: YES
Provenance & Taxonomy
Porthidium nasuta [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
aureus ATCC 25923 and S
PaperPubMed PMID: 22251437 PMID22251437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22251437/
RECORD: Rec_0366644 VERIFIED: YES
Provenance & Taxonomy
Porthidium nasuta [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PaperPubMed PMID: 22251437 PMID22251437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22251437/
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