Peptide Database

Peptide NameSynthetic Cercropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC186H315N53O48

DescriptionStandard

        KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAKG
    

Molecular Weight4061.82 Da

Isoelectric Point (pI)10.39

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1515

GRAVY Index-0.08

Hydrophobic Moment 0.80

Boman Index0.05

Instability Index14.12

Aliphatic Index 105.26

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1658.25

LogP -13.48

H-bond Donors 56.0

H-bond Acceptors 54.0

Rotatable Bonds 143.0

Heavy Atoms 287.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017227 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic Cercropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Anti-Trypanosoma cruzi

TargetTrypanosoma cruzi DM28

Activity140 μM

MethodMicroscopy (Neubauer hemocytometer)

RECORD: Rec_0071953 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic Cercropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Anti-Trypanosoma cruzi

TargetTrypanosoma cruzi Gainesville

Activity240 μM

MethodMicroscopy (Neubauer hemocytometer)

RECORD: Rec_0103346 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antitrypanosomal

RECORD: Rec_0137431 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic Cercropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Anti-Trypanosoma cruzi

TargetTrypanosoma cruzi Y

Activity150 μM

MethodMicroscopy (Neubauer hemocytometer)

RECORD: Rec_0191484 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial