Peptide Database

Peptide Name[I10]-Huwentoxin-II

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Venom / Toxin ▸ General toxin ▸ huwentoxin-2 family

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC188H303N49O51S7

DescriptionStandard

        LFECSFSCEIEKEGDKPCKKKKCKGGWKCKFNMCVKV
    

Molecular Weight4290.17 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.1271

GRAVY Index-0.63

Hydrophobic Moment 0.60

Boman Index-0.19

Instability Index40.39

Aliphatic Index 36.76

Aromaticity 0.1081

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1648.17

LogP -13.48

H-bond Donors 62.0

H-bond Acceptors 63.0

Rotatable Bonds 153.0

Heavy Atoms 295.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0241930 VERIFIED: NO

Provenance & Taxonomy

OrganismSelenocosmia huwena [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-18; 8-29; 23-34

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0311011 VERIFIED: YES

Provenance & Taxonomy

OrganismHaplopelma schmidti [Animal]

Familyhuwentoxin-2 family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-18; 8-29; 23-34

Bio-Activity Profile

Function

Toxin Venom huwentoxin-2 family Pathogenesis-associated