Peptide Database

Peptide NameIFN-α5

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length168 amino acids

Chemical FormulaC868H1360N236O263S12

DescriptionStandard

        LGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLEACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSANLQERLRRKE
    

Molecular Weight19694.29 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-3.98

Net Charge (pH 7.4) -4.44

Charge Density (pH 7.0) -0.0237

GRAVY Index-0.43

Hydrophobic Moment 0.64

Boman Index-0.07

Instability Index55.83

Aliphatic Index 77.20

Aromaticity 0.1012

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8149.03

LogP -82.46

H-bond Donors 285.0

H-bond Acceptors 274.0

Rotatable Bonds 667.0

Heavy Atoms 1379.0

Ring Count 27.0

Amide Bonds 186.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322891 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 3 and 101, and 31 and 141

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)