Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length222 amino acids

Chemical FormulaC1111H1709N257O342S9

DescriptionStandard

        KQIDDLAEVDYSLSSLPAVFQPFIDLDLKGMVSPAGNYTDSPYVAASFTIPDQSNSMLHLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQPLFTLNIAANTSISLNIFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANGK
    

Molecular Weight24426.55 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-16.05

Net Charge (pH 7.4) -16.44

Charge Density (pH 7.0) -0.0723

GRAVY Index0.28

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index45.75

Aliphatic Index 100.18

Aromaticity 0.1126

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392238 VERIFIED: NO

Provenance & Taxonomy

OrganismNotiomystis cincta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria