Peptide Database

Peptide NameSS-I

Function Ontology

Antiviral

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC215H316N56O60S7

DescriptionStandard

        FVVWGCADYRGSCRTACFAYEYSLGAKGCADGYICCVPNTFRLM
    

Molecular Weight4869.60 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0159

GRAVY Index0.34

Hydrophobic Moment 0.46

Boman Index0.17

Instability Index11.22

Aliphatic Index 57.73

Aromaticity 0.1818

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1850.17

LogP -16.95

H-bond Donors 73.0

H-bond Acceptors 68.0

Rotatable Bonds 149.0

Heavy Atoms 338.0

Ring Count 10.0

Amide Bonds 44.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0062568 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on European fire salamander [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

Targeted SARS-CoV-2

Activity2.7 μM

MethodEC50

RECORD: Rec_0167907 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on European fire salamander [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Toxicity

TargetVero CCL-81 cells

Activity10 μM

MethodLC50