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MYP_113879
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Basic Information
Bifunctional adenosylcobalamin biosynthesis protein CobU (145-162), P1c9k
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C93H158N38O24
Standard
Sequence
NRLARHFRDIAGRVNQRL
Physicochemical Analysis
2192.49 Da
12.00
3.85
3.59
0.2138
-0.97
0.90
-0.49
10.19
92.22
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1062.77
-11.88
39.0
29.0
75.0
155.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0258720 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 8530
40-50 %
Growth inhibition assay at 22 μM peptide
PaperPrimary study of P1c9k, a CobU-derived synthetic peptide; PMID:15822124. PMID15822124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15822124/
RECORD: Rec_0278422 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 8530
40-50 %
Growth inhibition assay at 11 μM peptide
PaperPrimary study of P1c9k, a CobU-derived synthetic peptide; PMID:15822124. PMID15822124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15822124/
RECORD: Rec_0312807 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Non-hemolytic
rat erythrocytes
Hemolysis assay (no detectable hemolysis)
Paperhttps://pubmed.ncbi.nlm.nih.gov/15822124/ PMID15822124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15822124/
RECORD: Rec_0397011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 8530
30-40 %
Growth inhibition assay at 4.5 μM peptide
PaperPrimary study of P1c9k, a CobU-derived synthetic peptide; PMID:15822124. PMID15822124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15822124/
RECORD: Rec_0418511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Non-hemolytic
rat erythrocytes
Hemolysis assay (no detectable hemolysis)
PaperPrimary study of P1c9k, a CobU-derived synthetic peptide; PMID:15822124. PMID15822124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15822124/
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