Peptide Database

Peptide NameAlloferon-1 [H1A]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC49H74N20O16

DescriptionStandard

        AGVSGHGQHGVHG
    

Molecular Weight1199.24 Da

Isoelectric Point (pI)7.06

Net Charge (pH 7.0)0.06

Net Charge (pH 7.4) -0.28

Charge Density (pH 7.0) 0.0044

GRAVY Index-0.44

Hydrophobic Moment 0.26

Boman Index0.23

Instability Index-14.70

Aliphatic Index 52.31

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 561.88

LogP -9.14

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 37.0

Heavy Atoms 85.0

Ring Count 3.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368590 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlloferon

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetCoxsackie virus 971 PT(971 PT CVB2):inhibition of virus replication in LLC-MK2 cells

Activity358 μg/mL

MethodIC50

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