Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC124H203N43O46

DescriptionStandard

        TAAGDARANAVAKAGLHDLNIETDTERNH
    

Molecular Weight3032.20 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-2.42

Net Charge (pH 7.4) -2.72

Charge Density (pH 7.0) -0.0834

GRAVY Index-0.73

Hydrophobic Moment 0.33

Boman Index-0.14

Instability Index45.67

Aliphatic Index 74.48

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1461.76

LogP -20.32

H-bond Donors 50.0

H-bond Acceptors 46.0

Rotatable Bonds 101.0

Heavy Atoms 213.0

Ring Count 2.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211310 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 37.9%, E 6.9%, T 34.5%, C 20.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0385430 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyHeptad repeat peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsScrambled sequence control

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); Vero

MethodPlaque assay

PaperAnalysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and B. | Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M. | J Gen Virol. 2006 | PMID:16603508 PMID16603508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16603508/