Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length304 amino acids

Chemical FormulaC1453H2307N403O465S4

DescriptionStandard

        MFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFAESDANKIMIDRLEKILNGEMQPTDTDKRFYTHEIRELERYRNLGIKDGIIPDNQGDVWNNTHTATLEDYKINERNEPLYTPDAIQAAEEQAKREYL
    

Molecular Weight32989.54 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-13.01

Net Charge (pH 7.4) -13.56

Charge Density (pH 7.0) -0.0428

GRAVY Index-0.47

Hydrophobic Moment 0.77

Boman Index-0.01

Instability Index33.96

Aliphatic Index 83.49

Aromaticity 0.0559

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0350919 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli