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MYP_113756
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Basic Information
CPRF-Eb (caerulein precursor-related fragment; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
31 amino acids
C136H234N38O41
Standard
Sequence
GLGSFLKNAIKIAGKVGSTIGKVADAIGNKE
Physicochemical Analysis
3057.54 Da
9.83
2.76
2.55
0.0892
0.19
0.66
0.17
-10.07
107.10
0.0323
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1287.89
-14.26
44.0
44.0
109.0
215.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105912 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5 μM
MIC
PMID14499272 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499272/
RECORD: Rec_0167718 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0184858 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
>100 μM
MIC
PaperAntimicrobial peptides from ranid frogs: taxonomic and phylogenetic markers and a potential source of new therapeutic agents
RECORD: Rec_0224614 VERIFIED: YES
Provenance & Taxonomy
Pelophylax esculentus [Animal]
CPRF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5.0 μM
MIC
PaperM.F. Ali et al. / Peptides 24 (2003) 955-961. Characterization of novel antimicrobial peptides from the skins of frogs of the Rana esculenta complex
RECORD: Rec_0227848 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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