Peptide Database

Peptide NameDefensin related cryptdin 23, partial [synthetic Construct].

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC445H734N132O145S8

DescriptionStandard

        MKTLVLLSALILLAFQVQADPIQNTDEETKTEEQPGKEDQAVSVSFGDPEGSSLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLIYTLCCR
    

Molecular Weight10509.91 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0156

GRAVY Index-0.51

Hydrophobic Moment 0.59

Boman Index-0.16

Instability Index45.27

Aliphatic Index 78.60

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4538.50

LogP -51.38

H-bond Donors 164.0

H-bond Acceptors 153.0

Rotatable Bonds 361.0

Heavy Atoms 730.0

Ring Count 8.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082169 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0261001 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic