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MYP_113706
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Basic Information
C-6 (analog of P18)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C97H153N23O16
Standard
Sequence
KWKLFKKIPKFLHLA
Physicochemical Analysis
1897.40 Da
10.60
4.84
4.58
0.3228
-0.13
0.82
0.04
-13.93
110.67
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
636.50
1.72
22.0
22.0
64.0
136.0
6.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0354381 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME hybrid peptide family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperShin SY et al. Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide P18 and its analogs. J Pept Res. 2001;58(6):504-514. DOI:10.1034/j.1399-3011.2001.00934.x. PMID:12005420.
RECORD: Rec_0361471 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
α-helical synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Normal cells NIH 3T3
100 μM
IC50
PaperAntibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. J Pept Res. 2001 Dec;58(6):504-14. doi: 10.1034/j.1399-3011.2001.00934.x. PMID: 12005420. PMID12005420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005420/
RECORD: Rec_0393955 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperShin SY et al. Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide P18 and its analogs. J Pept Res. 2001;58(6):504-514. DOI:10.1034/j.1399-3011.2001.00934.x. PMID:12005420.
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