Peptide Database

Peptide NameBeta-defensin 103

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC222H385N79O64S6

DescriptionStandard

        NGGIINTLQRYYCRIRSGRCALLSCLPKEEQIGRCSSTGRKCCRRKK
    

Molecular Weight5377.31 Da

Isoelectric Point (pI)10.10

Net Charge (pH 7.0)9.70

Net Charge (pH 7.4) 9.40

Charge Density (pH 7.0) 0.2064

GRAVY Index-0.71

Hydrophobic Moment 0.75

Boman Index-0.35

Instability Index63.55

Aliphatic Index 68.51

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2401.21

LogP -30.41

H-bond Donors 95.0

H-bond Acceptors 80.0

Rotatable Bonds 188.0

Heavy Atoms 371.0

Ring Count 3.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022279 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence