Peptide Database

Peptide NameUrokinase

Function Ontology

Hemostasis ▸ Fibrinolytic activity

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1263H1971N349O377S18

DescriptionStandard

        KPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLMSPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYT
    

Molecular Weight28653.44 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)5.27

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.46

Hydrophobic Moment 0.51

Boman Index-0.03

Instability Index45.51

Aliphatic Index 68.43

Aromaticity 0.0941

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40630.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029624 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyFibrinolytic protein

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Thrombolytic Fibrinolytic

Half-Life12 min

PaperPubMed-linked source references: PMID:26876783; PMID:25231010; PMID:24140055; PMID:23482705; PMID:22817872; PMID:20420509; PMID:18030361; PMID:15112999; PMID:25460592 PMID26876783;25231010;24140055;23482705;22817872;20420509;18030361;15112999;25460592 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26876783/ PatentUS4258030