Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H273N49O58S2

DescriptionStandard

        KCNTATCVTQRLADFLIRSSNTVGTVYSPTNVGSNTY
    

Molecular Weight3983.40 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index-0.18

Hydrophobic Moment 0.68

Boman Index-0.00

Instability Index8.12

Aliphatic Index 68.38

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1767.69

LogP -26.05

H-bond Donors 65.0

H-bond Acceptors 62.0

Rotatable Bonds 126.0

Heavy Atoms 278.0

Ring Count 4.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084381 VERIFIED: YES

Provenance & Taxonomy

OrganismLepisosteus oculatus [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)