Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC740H1164N218O218S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQSLRSLLVELKVQYAGAVLMAHHDVAPKACPSFNLKRWWEKNELVTSDRG
    

Molecular Weight16826.94 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0199

GRAVY Index-0.39

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index42.60

Aliphatic Index 75.50

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7050.36

LogP -73.58

H-bond Donors 248.0

H-bond Acceptors 234.0

Rotatable Bonds 562.0

Heavy Atoms 1183.0

Ring Count 26.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323787 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage 117 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic