Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC391H606N106O106S10

DescriptionStandard

        MAKFASIITLLFAALVLFASLEAPTMVEAQKLCQRPSGTWSGVCGNNGACKNQCINLEKARHGSCNYVFPYHRCICYFPC
    

Molecular Weight8808.29 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)3.60

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0450

GRAVY Index0.28

Hydrophobic Moment 0.45

Boman Index0.16

Instability Index23.90

Aliphatic Index 79.38

Aromaticity 0.1125

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3369.14

LogP -31.97

H-bond Donors 123.0

H-bond Acceptors 122.0

Rotatable Bonds 281.0

Heavy Atoms 613.0

Ring Count 16.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041732 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence