Peptide Database

Peptide Namehepcidin TH2-3

Function Ontology

—

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC88H141N31O24S6

DescriptionStandard

        QSHLSLCRWCCKCCHNKGC
    

Molecular Weight2209.64 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.1512

GRAVY Index-0.32

Hydrophobic Moment 0.54

Boman Index-0.17

Instability Index100.36

Aliphatic Index 41.05

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.85

LogP -11.27

H-bond Donors 38.0

H-bond Acceptors 35.0

Rotatable Bonds 72.0

Heavy Atoms 149.0

Ring Count 4.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0002986 VERIFIED: YES

Provenance & Taxonomy

OrganismPlecoglossus altivelis [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)