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MYP_113537
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Basic Information
CAP7 (2-31), CAP18 (136-165), CAP18-MP(FV)(2-31)
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C171H304N54O36
Standard
Sequence
LRKRLRKFRNKIKEKLKKIGQKIQGFVPKL
Physicochemical Analysis
3692.58 Da
12.00
11.75
11.54
0.3918
-1.03
0.67
-0.46
31.99
100.67
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1546.78
-9.82
55.0
48.0
140.0
261.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094333 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Non-hemolytic
Mouse erythrocytes
Hemolysis assay (no detectable hemolysis at 25 μM)
PaperLi Z et al. In vitro and in vivo antibacterial activity and toxicity of the peptide CAP18. Scientific Reports. 2016;6:39189. DOI:10.1038/srep39189. PMID:27925615. PMID27925615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27925615/
RECORD: Rec_0114064 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Stenotrophomonas maltophilia CGMCC 1.1788
2.99 μM
LC (agar diffusion/inhibition-zone assay)
PaperLi Z et al. In vitro and in vivo antibacterial activity and toxicity of the peptide CAP18. Scientific Reports. 2016;6:39189. DOI:10.1038/srep39189. PMID:27925615. PMID27925615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27925615/
RECORD: Rec_0131457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus P1383
1.35 μM
LC (agar diffusion/inhibition-zone assay)
PaperLi Z et al. In vitro and in vivo antibacterial activity and toxicity of the peptide CAP18. Scientific Reports. 2016;6:39189. DOI:10.1038/srep39189. PMID:27925615. PMID27925615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27925615/
RECORD: Rec_0133606 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
2.1 μM
LC (agar diffusion/inhibition-zone assay)
PaperLi Z et al. In vitro and in vivo antibacterial activity and toxicity of the peptide CAP18. Scientific Reports. 2016;6:39189. DOI:10.1038/srep39189. PMID:27925615. PMID27925615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27925615/
RECORD: Rec_0137479 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
1.33 μM
LC (agar diffusion/inhibition-zone assay)
PaperLi Z et al. In vitro and in vivo antibacterial activity and toxicity of the peptide CAP18. Scientific Reports. 2016;6:39189. DOI:10.1038/srep39189. PMID:27925615. PMID27925615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27925615/
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