Peptide Database

Peptide NamePhyllokininogen-1

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC206H312N56O82

DescriptionStandard

        EEEKREAEEEENEDEIEEESDEKKRESPDRPPGFSPFRIY
    

Molecular Weight4885.01 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-11.12

Net Charge (pH 7.4) -11.33

Charge Density (pH 7.0) -0.2781

GRAVY Index-2.26

Hydrophobic Moment 0.34

Boman Index-0.57

Instability Index145.99

Aliphatic Index 22.00

Aromaticity 0.0750

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2284.13

LogP -23.80

H-bond Donors 75.0

H-bond Acceptors 71.0

Rotatable Bonds 169.0

Heavy Atoms 344.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079388 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyPhyllokininogen

Tax ID317381

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods32:4-hydroxyproline; 40:Sulfotyrosine

Bio-Activity Profile

Function

Vasoactive Vasodilator Receptor modulation

Targetvitro relaxation of rat arterial smooth muscle

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0234688 VERIFIED: YES