Peptide Database

Peptide NameCecropin A

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC184H312N56O45

DescriptionStandard

        RWKVFKKIEKVGRHIRDGVIKAGPAITVVGQATALGK
    

Molecular Weight4028.79 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)6.85

Net Charge (pH 7.4) 6.58

Charge Density (pH 7.0) 0.1850

GRAVY Index-0.10

Hydrophobic Moment 0.91

Boman Index-0.02

Instability Index39.25

Aliphatic Index 102.70

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1646.57

LogP -13.03

H-bond Donors 59.0

H-bond Acceptors 53.0

Rotatable Bonds 139.0

Heavy Atoms 285.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086600 VERIFIED: YES

Provenance & Taxonomy

OrganismHyphantria cunea [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)